More than a kilometre of new sewer main is being laid in Godmanchester to connect new homes to the sewerage system.
The work in Cow Lane, and Cambridge Road, is needed to connect a new housing development.
The work will begin on Monday (April 4) for 12 weeks, finishing on Monday, June 27.
Sarah Dobson, Anglian Water spokesman, said: “This project is needed to bring water recycling services to new homes. We are required to extend our network to allow new homes to be connected to the mains water and sewerage services.
“We appreciate that the work will cause some disruption to local residents, and we apologise for that. We’ve been working closely with the Highways authority to keep the disruption to a minimum.
“Diversion signs will be in place and we will be working extended hours wherever possible - including some overnight work - to complete the work as quickly as possible.”
There will be overnight slip lane closures in place for the safety of the public and the Anglian Water workforce on the A14 east and west bound slip roads. The slip lanes will be reduced to one lane between 8pm and 6am for four nights. Advanced warning signs will be in place.
The spokesman added: “Traffic lights will be in place in Cow Lane and Cambridge Road from Monday (April, 4) to help keep traffic moving.”